بیماران با جراحی قلب بزرگسالان با طیف سنجی مادون قرمز نزدیک

0
Near-Infrared Spectroscopy Adult Cardiac Surgery Patients: Systematic Review and Meta-Analysis

Objectives: To identify the normal baseline preoperative range of cerebral tissue oxygen saturation (SctO2) derived using near-infrared

spectroscopy (NIRS) and the efficacy of perioperative interventions designed to modulate SctO2 in cardiac surgical patients

Design: Systematic review and meta-analysis of relevant randomized controlled trials (RCTs) extracted from the Medline, Embase, and

Cochrane Central Register of Controlled Trials databases

Setting: Hospitals performing cardiac surgery

Participants: The study comprised 953 participants from 11RCTs

Interventions: Interventions included the following

(1) SctO2 monitoring protocol compared with no monitoring

(2) use of cardiopulmonary by pass

(CPB) compared with no CPB (3)

(normothermic CPB compared with hypothermic CPB (4

  (5) glyceryl trinitrate during surgery compared with placebo

 (midazolam during induction of anesthesia compared with propofol (6

(7) sevoflurane anesthesia compared with total intravenous anesthesia

 (sevoflurane anesthesia compared with propofol-based anesthesia ;and (8

norepinephrine during CPB compared with phenylephrine

Measurements and Main Results: Eleven RCTs with 953 participants measured baseline preoperative SctO2 using NIRS

The pooled mean baseline SctO2 was 66.4% (95%CI65.0-67.7), generating a reference range of 51.0%to81.8%

Four interventions (1,3,4, and 6 described in the Interventions section above) increased intraoperative SctO2 across the majority of reported time points

Postoperative follow-up of SctO2 occurred in only 1 study, and postoperative cognitive assessment correlating SctO2 with cognitive function was applied in only 4 studies using variable methodology

Conclusions: The authors have established that reference values for baseline NIRS-derived SctO2 in cardiac surgery patients are varied and have identified interventions that modulate SctO2. This information opens the door to standardized research and interventional studies in this field

بیماران با جراحی قلب بزرگسالان با طیف سنجی مادون قرمز نزدیک: مرور سیستماتیک و فراتحلیل
واکنش خود را انتخاب کنید!
دیدگاهی بنویسید

ایمیل شما نمایش داده نخواهد شد.